Anti-neovascular therapy by targeted liposomes

Multifunctional Liposomes for Enhanced Anti- Cancer Therapy

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Large anti-HER2/neu liposomes for potential targeted intraperitoneal therapy of micrometastatic cancer.

UNLABELLED Effective targeting and killing of intraperitoneally disseminated micrometastases remains a challenge. OBJECTIVE/METHODS  In this work, we evaluated the potential of antibody-labeled PEGylated large liposomes as vehicles for direct intraperitoneal (i.p.) drug delivery with the aim to enhance the tumor-to-normal organ ratio and to improve the bioexposure of cancer cells to the deliv...

Active Targeting Liposomes: Promising Approach for Tumor-Targeted Therapy

Xiaoyi Wang1 and Weiyue Lu1-3* 1Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai 201203, PR China 2State Key Laboratory of Medical Neurobiology, The Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, PR China 3State Key Laboratory of Molecular Engineeri...

Targeted Multimodal Liposomes for Imaging and Radionuclide Therapy

GERBEN A. KONING*, WILLEM MULDER, GUSTAV J. STRIJKERS, KLAAS NICOLAY, SANDER ZIELHUIS, FRANK NIJSEN, MARJAN M. FRETZ, GERT STORM and GERARD C. KRIJGER Department of Radiation, Radioisotopes and Reactors, Delft University of Technology, Mekelweg 15, 2629-JB, Delft, The Netherlands, Department of Biomedical NMR, Eindhoven University of Technology, The Netherlands, Department of Nuclear Medicine, ...

Promising Treatment Strategies for Neovascular AMD: Anti-VEGF Therapy